Resurrection was established in 1936. Beginning in 1934, a group of Catholics in the section of West Mifflin called Homeville organized to work for a local parish. A year later, they presented a petition to the bishop for a parish. On November 7, 1935, the bishop instructed the Missionary Confraternity of Christian Doctrine (MCCD) to take over the care of Homeville until a regular parish could be established. The MCCD was formed by the diocese to minister to Catholics in isolated areas who did not have easy access to a parish. On April 12, 1936, the first Mass in the new parish was celebrated in the Homeville firehall. On September 30, 1937, a resident pastor was assigned to the parish.
Groundbreaking for a new church took place on May 24, 1938. The church was dedicated on November 11, 1938. The church served the congregation for twenty five years, surviving a fire in 1946.
Beginning in 1960, the parish began a renovation of the entire parish plant. The first step was the purchase of additional land and the construction of a parish school. The school was built and opened in 1962. On September 3, 1963, ground was broken for a new church with an attached convent. The cornerstone of the new church was laid on October 11, 1964, and the church was dedicated on April 11, 1965. The old church was converted to a social center.
With the turn of the century, trends in the Diocese of Pittsburgh began to reveal a decline in Mass attendance and sacramental participation. At the same time, the number of priests available for parish ministry also began to decline.
To address these challenges, Bishop David Zubik announced on April 12, 2015 a new diocesan initiative, On Mission for The Church Alive!, a consultative strategic planning process designed to foster viable, sustainable and vibrant parishes. As part of this process, the Bishop, in consultation with the faithful, began to consider new models of parish life based on pastoral needs, financial and temporal resources and available clergy.
In 2018, following the period of consultation, parishes were grouped together and served by a single clergy team to eventually form one new parish.
During this transition period, Resurrection Parish remained an independent parish while sharing clergy and staff and eventually publishing a joint bulletin with the other parishes. This ended on July 1, 2020 when Resurrection Parish merged with the parishes of St. Maximilian Kolbe Parish, Homestead/Munhall; the Duquesne parishes of St. Joseph and Christ the Light of the World; the West Mifflin parishes of Holy Trinity and St. Agnes; and the Munhall parishes of St. Rita and St. Therese of Lisieux to form the new St. Thomas the Apostle Parish. As part of the merger Resurrection Church initially remained open as part of the new parish.